Mercury (II) Stimulation of Malate Dehydrogenase Activity

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Mercury (II) Stimulation of Malate Dehydrogenase Activityti’

The reduction of NAD catalyzed by pig heart mitochondrial malate dehydrogenase can be stimulated by low concentrations, approximately 0.05 mM, of Hg-‘+. This activation is dependent on the presence of the substrate malate at the time the enzyme is exposed to Hg-‘-+. The stimulation is both pHand temperature-dependent, with maximum stimulation occurring near pH 8.8 and 30”. The activation is not...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1968

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)93616-1